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KPTIKaryopharm Therapeutics IncRunning, no new patients

A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Relapsed/Refractory Diffuse Large B-cell Lymphoma

1Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 6 insiders sold shares within a month

    Since May 14, 2026 · was worth 10, fading over time

    +1.3
Worry score1

Score over time

Stage
Phase 2/3
Patients
501 (planned)
Started
Sep 3, 2020
Main results expected
Dec 2026
Fully finished
Dec 2026
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Phase 2: Overall Response Rate (ORR): Based on Lugano Criteria 2014

    Measured over: From date of initial randomization to the date of disease progression or initiating a new DLBCL treatment (maximum of 5 years from randomization)

  • Phase 3: Progression-free Survival (PFS): Based on Lugano Criteria 2014

    Measured over: From date of initial randomization to the date of disease progression or death (maximum of 5 years from randomization)

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 10, now 1.3, since 2026-05-14, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT04442022 · record last updated 2026-10-02 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04442022) ↗