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KPTIKaryopharm Therapeutics IncSigning up patients

A Study of Selinexor (Seli) + Low-dose Dexamethasone (LDD) in Penta-refractory Multiple Myeloma (MM), Seli and Bortezomib + LDD in Triple-class Refractory MM.

Multiple Myeloma, Refractory

1Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 6 insiders sold shares within a month

    Since May 14, 2026 · was worth 10, fading over time

    +1.3
Worry score1

Score over time

Stage
Phase 2
Patients
127 (planned)
Started
Jul 1, 2020
Main results expected
Jan 2028
Fully finished
Jan 2028
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Overall Response Rate (ORR)

    Measured over: From the date of randomization up to death (approximately 60 months)

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 10, now 1.3, since 2026-05-14, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT04414475 · record last updated 2026-10-29 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04414475) ↗