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Not investment advice.

Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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ONCBeiGeneFinished

Anti-HER2 Bispecific Antibody Zanidatamab (ZW25) Activity in Combination With Chemotherapy With/Without Tislelizumab

Breast Cancer · Gastric Cancer · Gastroesophageal Junction Cancer

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 2 insiders sold shares within a month

    Since Aug 3, 2026 · was worth 5, fading over time

    +1.7
Worry score2

Score over time

Stage
Phase 1/2
Patients
71 (final count)
Started
Mar 23, 2020
Main results expected
Dec 7, 2023
Fully finished
Oct 31, 2024
Results posted
Sep 2, 2026

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Number of Participants Experiencing Adverse Events (AEs) and Serious Adverse Events (SAEs)

    Measured over: From the first dose of study drug(s) to 30 days after the last dose; up to approximately 42 months

  • Objective Response Rate (ORR)

    Measured over: Response was assessed every 6 weeks from cycle 1 day 1 for the first 36 weeks and then every 12 weeks thereafter; maximum time on study follow-up was 42months.

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.7, since 2026-08-03, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT04276493 · record last updated 2026-09-02 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04276493) ↗