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NVSNovartis PharmaceuticalsSigning up patients

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

Advanced Solid Tumor · Diffuse Large B Cell Lymphoma · Lymphoma, T-Cell · Mesothelioma, Malignant · Prostatic Neoplasms, Castration-Resistant · Endometrial Cancer · Ovarian Clear Cell Carcinoma · Metastatic Castration-resistant Prostate Cancer

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
300 (planned)
Started
Sep 18, 2019
Main results expected
Feb 27, 2030
Fully finished
Feb 27, 2030
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Tulmimetostat Monotherapy Phase 1: Frequency of Dose-limiting toxicities (DLTs)

    Measured over: DLTs assessed during Cycle 1 (cycle = 28 days)

  • Tulmimetostat Monotherapy Phase 2: Overall response rate (ORR)

    Measured over: Up to 30 months

  • Cohort M8 Part 1: Frequency of Dose-limiting toxicities (DLTs)

    Measured over: DLTs assessed during Cycle 1 (cycle = 28 days)

  • Cohort M8 Part 2: Prostate-Specific Antigen 50 (PSA50) Response

    Measured over: Up to 30 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT04104776 · record last updated 2026-08-19 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04104776) ↗