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MGNXMacroGenicsFinished

Combination Margetuximab, Retifanlimab, Tebotelimab, and Chemotherapy Phase 2/3 Trial in HER2+ Gastric/GEJ Cancer

Gastric Cancer · Gastroesophageal Junction Cancer · HER2-positive Gastric Cancer

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 2/3
Patients
82 (final count)
Started
Sep 30, 2019
Main results expected
Jan 15, 2024
Fully finished
Mar 25, 2025
Results posted
Apr 22, 2025

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Number of Participants With Adverse Events of Margetuximab Plus Retifanlimab in Cohort A, as Assessed by CTCAE v5.0

    Measured over: Throughout the study, an average of 11 months.

  • Objective Response Rate (ORR) for Non-microsatellite Instability-high (Non-MSI-H) Participants (Cohort A) Using Investigator-assessed Radiology Reviews

    Measured over: Throughout the study, an average of 11 months.

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT04082364 · record last updated 2025-06-08 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04082364) ↗