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ARVNArvinas Inc.Finished

Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer

Prostate Cancer Metastatic

11Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • Main results were due Apr 2024, none posted yet

    Counts until it's fixed

    +10
  • 5 insiders sold shares within a month

    Since May 21, 2026 · was worth 10, fading over time

    +1.4
Worry score11

Score over time

Stage
Phase 1/2
Patients
248 (final count)
Started
Mar 1, 2019
Main results expected
Apr 29, 2024
Fully finished
Jan 27, 2025
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Part A: Incidence of Dose Limiting Toxicities of ARV-110

    Measured over: 28 Days

  • Part A: Number of Patients with Adverse Events as a measure of safety and tolerability of ARV-110

    Measured over: 28 Days

  • Part A: Incidence of laboratory abnormalities as a measure of safety and tolerability of ARV-110

    Measured over: 28 Days

  • Part B: Measurement of PSA response rate per PCWG3 accessing anti-tumor activity of ARV-110

    Measured over: 12 Weeks

  • Part B: Measurement of overall RECIST response rate accessing the anti-tumor activity of ARV-110

    Measured over: 12 Weeks

  • Part B: To evaluate the clinical anti-tumor activity of ARV-110 in patients with mCRPC

    Measured over: 12 Weeks

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • results_overdue: base 10, now 10, since 2024-04-29, no fading
  • insider_selling_cluster: base 10, now 1.4, since 2026-05-21, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT03888612 · record last updated 2025-04-01 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT03888612) ↗