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CRDFCardiff OncologyFinished

Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a KRAS Mutation

Metastatic Colorectal Cancer · KRAS Gene Mutation

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
68 (final count)
Started
Jun 24, 2019
Main results expected
Jan 29, 2024
Fully finished
Jan 29, 2024
Results posted
Mar 4, 2025

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Phase 1b: Number of Participants With Dose-limiting Toxicities (DLTs)

    Measured over: Up to Day 28

  • Phase 1b: Number of Participants With Treatment-emergent Adverse Events (TEAEs)

    Measured over: Up to a maximum of 81 weeks

  • All-Treated Analysis Set: Objective Response Rate (ORR)

    Measured over: Up to a maximum of 131 weeks

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT03829410 · record last updated 2025-03-04 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT03829410) ↗