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Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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BMYBristol-Myers SquibbFinished

A Study of BMS-986253 in Combination With Nivolumab or Nivolumab Plus Ipilimumab in Advanced Cancers

Cancer · Melanoma

3Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 2 insiders sold shares within a month

    Since Sep 9, 2026 · was worth 5, fading over time

    +2.6
Worry score3

Score over time

Stage
Phase 1/2
Patients
281 (final count)
Started
Feb 12, 2018
Main results expected
Apr 26, 2024
Fully finished
Dec 4, 2025
Results posted
Jun 19, 2025

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Number of Participants Experiencing Adverse Events (AEs) - Part 1

    Measured over: From first dose up to 100 days after last dose (up to 65 months)

  • Number of Participants Experiencing Serious Adverse Events (SAEs) - Part 1

    Measured over: From first dose up to 100 days after last dose (up to 65 months)

  • Number of Participants Experiencing Dose Limiting Toxicities (DLTs) - Part 1

    Measured over: From first dose up to 100 days after last dose (up to 65 months)

  • Number of Participants Experiencing Adverse Events (AEs) Leading to Discontinuation - Part 1

    Measured over: From first dose up to 100 days after last dose (up to 65 months)

  • Number of Participants Who Died - Part 1

    Measured over: From first dose up to 100 days after last dose (up to 65 months)

  • Most Frequently Reported Grade 3 and Grade 4 Laboratory Test Results - Part 1

    Measured over: From first dose up to 30 days after last dose (up to 63 months)

  • Objective Response Rate (ORR) - Part 2

    Measured over: From the date of the first dose to the date of first objectively documented progression per RECIST v1.1 or the date of subsequent therapy, whichever occurred first (up to approximately 22 months)

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 2.6, since 2026-09-09, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT03400332 · record last updated 2026-02-24 · checked 2026-11-09 15:42 UTC

See the official record on ClinicalTrials.gov (NCT03400332) ↗