A Study of BMS-986253 in Combination With Nivolumab or Nivolumab Plus Ipilimumab in Advanced Cancers
Cancer · Melanoma
No strong warning signs right now. The score counts warning signs; it is not a prediction.
Why this score
- +2.6
2 insiders sold shares within a month
Since Sep 9, 2026 · was worth 5, fading over time
Score over time
- Stage
- Phase 1/2
- Patients
- 281 (final count)
- Started
- Feb 12, 2018
- Main results expected
- Apr 26, 2024
- Fully finished
- Dec 4, 2025
- Results posted
- Jun 19, 2025
What counts as success
The trial's main goal(s), called the “primary outcome.”
Number of Participants Experiencing Adverse Events (AEs) - Part 1
Measured over: From first dose up to 100 days after last dose (up to 65 months)
Number of Participants Experiencing Serious Adverse Events (SAEs) - Part 1
Measured over: From first dose up to 100 days after last dose (up to 65 months)
Number of Participants Experiencing Dose Limiting Toxicities (DLTs) - Part 1
Measured over: From first dose up to 100 days after last dose (up to 65 months)
Number of Participants Experiencing Adverse Events (AEs) Leading to Discontinuation - Part 1
Measured over: From first dose up to 100 days after last dose (up to 65 months)
Number of Participants Who Died - Part 1
Measured over: From first dose up to 100 days after last dose (up to 65 months)
Most Frequently Reported Grade 3 and Grade 4 Laboratory Test Results - Part 1
Measured over: From first dose up to 30 days after last dose (up to 63 months)
Objective Response Rate (ORR) - Part 2
Measured over: From the date of the first dose to the date of first objectively documented progression per RECIST v1.1 or the date of subsequent therapy, whichever occurred first (up to approximately 22 months)
Changes Tremor has spotted
Show details (technical version)
Score inputs
- insider_selling_cluster: base 5, now 2.6, since 2026-09-09, fades (half-life)
Raw record changes
- none yet
Trial ID NCT03400332 · record last updated 2026-02-24 · checked 2026-11-09 15:42 UTC