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BMYJuno Therapeutics, a Subsidiary of CelgeneRunning, no new patients

Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)

Leukemia, Lymphocytic, Chronic, B-Cell · Lymphoma, Small Lymphocytic

3Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 2 insiders sold shares within a month

    Since Sep 9, 2026 · was worth 5, fading over time

    +2.6
Worry score3

Score over time

Stage
Phase 1/2
Patients
320 (planned)
Started
Nov 27, 2017
Main results expected
Nov 26, 2027
Fully finished
Nov 26, 2027
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Phase 1 JCAR017 monotherapy arm: adverse events

    Measured over: Up to 48 months post treatment

  • Phase 1 JCAR017 monotherapy arm: laboratory abnormalities

    Measured over: Up to 48 months post treatment

  • Phase 1 JCAR017 and ibrutinib combination dose escalation therapy arm: adverse events

    Measured over: Up to 48 months post treatment

  • Phase 1 JCAR017 and ibrutinib combination dose escalation therapy arm: laboratory abnormalities

    Measured over: Up to 48 months post treatment

  • Phase 1 JCAR017 and ibrutinib combination dose expansion therapy arm

    Measured over: Through post treatment up to Month 48

  • Phase 1 JCAR017 and venetoclax combination dose escalation therapy arm: adverse events

    Measured over: Up to 48 months post treatment

  • Phase 1 JCAR017 and venetoclax combination dose escalation therapy arm: laboratory abnormalities

    Measured over: Up to 48 months post treatment

  • Phase 1 JCAR017 and venetoclax combination dose expansion therapy arm

    Measured over: Through post treatment up to Month 48

  • Phase 2 JCAR017 monotherapy expansion arm

    Measured over: Through post treatment up to Month 48

  • Phase 2 JCAR017 Double exposed monotherapy expansion arm: overall response rate (ORR)

    Measured over: Up to approximately 24 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 2.6, since 2026-09-09, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT03331198 · record last updated 2026-07-06 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT03331198) ↗