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AZNAstraZenecaRunning, no new patients

Durvalumab ± Tremelimumab in Combination With Platinum Based Chemotherapy in Untreated Extensive-Stage Small Cell Lung Cancer (CASPIAN)

Small Cell Lung Carcinoma Extensive Disease

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 3
Patients
987 (final count)
Started
Mar 27, 2017
Main results expected
Jan 27, 2020
Fully finished
Dec 31, 2026
Results posted
Mar 4, 2021

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Overall Survival (OS) in the Global Cohort; Assessed at Global Cohort Interim Analysis; D + EP Compared With EP

    Measured over: From baseline until death due to any cause. Assessed until global cohort interim analysis DCO (maximum of approximately 23 months).

  • OS in the Global Cohort; Assessed at Global Cohort Final Analysis; D + EP Compared With EP and D + T + EP Compared With EP

    Measured over: From baseline until death due to any cause. Assessed until global cohort final analysis DCO (maximum of approximately 33 months).

  • OS in the China Cohort; Assessed at China Cohort First Analysis; D + EP Compared With EP

    Measured over: From baseline until death due to any cause. Assessed until China cohort first analysis DCO (maximum of approximately 19 months).

  • OS in the China Cohort; Assessed at China Cohort Second Analysis; D + EP Compared With EP and D + T + EP Compared With EP

    Measured over: From baseline until death due to any cause. Assessed until China cohort second analysis DCO (maximum of approximately 29 months).

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT03043872 · record last updated 2026-07-16 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT03043872) ↗