A Study to Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction Chemotherapy
Leukemia, Myeloid, Acute
No strong warning signs right now. The score counts warning signs; it is not a prediction.
Why this score
- +2.6
2 insiders sold shares within a month
Since Sep 9, 2026 · was worth 5, fading over time
Score over time
- Stage
- Phase 1/2
- Patients
- 130 (final count)
- Started
- Jun 3, 2016
- Main results expected
- Aug 2, 2018
- Fully finished
- Sep 30, 2026
- Results posted
- Nov 22, 2022
What counts as success
The trial's main goal(s), called the “primary outcome.”
The Number of Participants Experiencing Dose-limiting Toxicities (DLTs): Phase 1B (Dose Finding Stage)
Measured over: From first dose to 28 days after first dose
The Number of Participants Experiencing Adverse Events: Phase 1B (Dose Finding and Expansion Stage)
Measured over: From first dose to 28 days after last dose (up to approximately 13 months)
Overall Response Rate: Phase 2 (Randomized Stage)
Measured over: From first dose up to approximately 26 months
Changes Tremor has spotted
Show details (technical version)
Score inputs
- insider_selling_cluster: base 5, now 2.6, since 2026-09-09, fades (half-life)
Raw record changes
- none yet
Trial ID NCT02677922 · record last updated 2026-02-19 · checked 2026-11-09 15:47 UTC